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Search Results for " beta receptor 2 "

Targets Recommended: Adenylyl cyclase Adrenergic Receptor AChR

28

抑制剂 & 化合物

5

天然产物

375

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10066	2',5'-Dideoxyadenosine	Adenylyl cyclase; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	2',5'-Dideoxyadenosine 是一种非竞争性腺苷酸环化酶抑制剂，通过结合 P 位点，IC50为 3 µM。它是核苷类似物，在心脏中发挥强大的抗肾上腺素作用。
T22852	ICI 89406 1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	ICI 89406 (1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea) 是一种选择性 β1 肾上腺素能受体拮抗剂，可用于 PET 用正电子发射器标记。
T23283	2-Methoxyidazoxan monohydrochloride RX 821002 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-Albizziin (2-Methoxyidazoxan monohydrochloride) 是高效的 alpha 2r 肾上腺素受体选择性拮抗剂，对 imidazoline 拮抗作用很小或没有。它对 (豚鼠) alpha 2D 肾上腺素受体 (pKd9.7) 的亲和力明显高于 (兔子) alpha 2A 肾上腺素受体 (pKd8.2)。
T12970	Solabegron GW 427353,3'-[[2-[(2R)-2-(3-氯苯基)-2-羟基乙基]氨基]乙基]氨基]-[1,1'-联苯基]-3-羧酸	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Solabegron (GW 427353) 是一种β3肾上腺素能受体 (β3-AR)的选择性激动剂, 在中国仓鼠卵巢细胞中测得 EC50=22 nM，可用于研究膀胱过度活跃和肠易激综合征。
T1726	SB-431542 4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物,SB 431542	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	SB-431542 是一种 ALK5/TGF-β type I Receptor 的抑制剂 (IC50=94 nM)，具有选择性。SB 431542 对 ALK4 和 ALK7 也有抑制活性，但对其他蛋白没有抑制作用。SB 431542 可以用于干细胞的诱导分化。
T8330	BIO-013077-01 6-(3-(6-甲基吡啶-2-基)-1H-吡唑-4-基)喹噁啉	TGF-beta/Smad	Stem Cells
	BIO-013077-01 是吡唑类TGF-β抑制剂。
T9220	Naftopidil hydrochloride 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil hydrochloride (BM-15275 hydrochloride) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力 Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T1244	Celiprolol hydrochloride Selecor,Selectrol,盐酸塞利洛尔	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Celiprolol hydrochloride (Selectrol) 是一种选择性肾上腺素受体调节剂，是一种选择性的和具有口服活性的β1肾上腺素受体拮抗剂，具有部分β2激动剂活性，具有降压和抗心绞痛的作用。
T6146	Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种选择性和 ATP 竞争性的AMPK 抑制剂，Ki 为 109 nM。它诱导自噬，通过靶向抑制 I 型受体ALK2，ALK3和ALK6来抑制 BMP 途径。
T9799	Serba-2	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Serba-2 是苯并吡喃选择性雌激素受体 β 的激动剂。
T80622	Trontinemab
	Trontinemab为一种双特异性人源IgG1-κ抗体，靶向Aβ前体蛋白(APP)与转铁蛋白受体p90, CD71 (TFRC)。该抗体主要应用于阿兹海默症研究。
T25190	Butoxamine hydrochloride NSC 106565,NSC106565,NSC-106565
	Butoxamine hydrochloride is a beta-2 selective adrenergic antagonist used primarily in animal and tissue experiments to characterize beta-2 receptor involvement and identify beta-2 receptors.
T0811L	Amisulpride hydrochloride APD-421,Amisulpride HCl,APD 421,APD421,Sultopride,氨磺必利盐酸盐
	Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.
T29518	Abediterol LAS100977,LAS 100977,LAS-100977
	Abediterol (LAS100977) is a new potent, long-acting inhaled beta (2) -adrenergic receptor agonist being developed for the treatment of asthma and chronic obstructive pulmonary disease.
T24380	L-796568 free base
	L-796568 free base is a β3 adrenergic receptor agonist potentially for the treatment of obesity. L-796568 is a potent full beta(3) agonist (EC50: 3.6 nM). It has 600-fold selectivity over the human beta(1) and beta(2) receptors.
T34079	Pirbuterol Acetate pirbuterol sulfate,EINECS 265-862-4,Maxair,Pirbuterol acetate (USAN)
	Pibuterol Acetate is a short-acting beta-2 adrenergic receptor agonist with bronchiectasis and is used as a respiratory activated quantitative inhaler in the treatment of asthma.
T27786	L-796568 dihydrochloride L 796568,L-796568,L796568
	L-796568, is a β3 adrenergic receptor agonist. L-796568 is a potent full beta(3) agonist (EC(50) = 3.6 nM, 94% activation) with >600-fold selectivity over the human beta(1) and beta(2) receptors, which also displays good oral bioavailability in several
T78567	Moprolol (±)-Moprolol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Moprolol ((±)-Moprolol)为β-肾上腺素能受体阻滞剂，主要应用于原发性高血压研究。
T69209	ZK-304709
	ZK-304709 is a potent multi-target tumor growth inhibitor with IC50 = nanomolar inhibitory activity to cyclin-dependent kinases 1, 2, 4, 7 and 9, as well as vascular endothelial growth factor receptor tyrosine kinase 1-3 and of platelet-derived growth factor receptor beta tyrosine kinase.
T70468	MK-8666
	MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.
T69953	MK-8666 Tris
	MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 Tris has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.
T76971	Trastuzumab beta
	Trastuzumab beta (ABP 980)是Trastuzumab的生物仿制药，靶向人表皮生长因子受体2 (HER2) 的单克隆抗体 (McAb)。该药物适用于研究HER2阳性转移性乳腺癌、早期乳腺癌 (EBC) 和转移性胃癌。
TP1662	Galanin Receptor Ligand M35
	The chimeric peptide M35 [galanin (1-13)-bradykinin(2-9) amide] is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. The radiolabelled M35 and perf
T69055	PD153035 nitrate
	PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also...
T75717	Disitertide diammonium
	Disitertide (P144) diammonium 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide diammonium 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T75716	Disitertide TFA
	Disitertide (P144) TFA 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide TFA 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T28157	Nephrin
	Nephrin is a cell surface signaling receptor protein that regulates podocyte function and plays a role in β-cell survival signaling; it is a protein necessary for the proper functioning of the renal filtration barrier. Nephrin belongs to a family of highl
T65598	Cefminox sodium
	Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ...

化合物

2',5'-Dideoxyadenosine

Cat.No: T10066

Target: Adenylyl cyclase, Adrenergic Receptor, AChR

Cat.No: T22852

Synonym: 1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea

Target: Adrenergic Receptor

2-Methoxyidazoxan monohydrochloride

Cat.No: T23283

Synonym: RX 821002 hydrochloride

Target: Adrenergic Receptor

Cat.No: T12970

Synonym: GW 427353,3'-[[2-[(2R)-2-(3-氯苯基)-2-羟基乙基]氨基]乙基]氨基]-[1,1'-联苯基]-3-羧酸

Target: Adrenergic Receptor

Cat.No: T1726

Synonym: 4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物,SB 431542

Target: ALK, TGF-beta/Smad

Cat.No: T8330

Synonym: 6-(3-(6-甲基吡啶-2-基)-1H-吡唑-4-基)喹噁啉

Target: TGF-beta/Smad

Naftopidil hydrochloride

Cat.No: T9220

Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride

Target: Adrenergic Receptor

Celiprolol hydrochloride

Cat.No: T1244

Synonym: Selecor,Selectrol,盐酸塞利洛尔

Target: Adrenergic Receptor

Dorsomorphin dihydrochloride

Cat.No: T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Cat.No: T9799

Target: Estrogen/progestogen Receptor

Cat.No: T80622

Butoxamine hydrochloride

Cat.No: T25190

Synonym: NSC 106565,NSC106565,NSC-106565

Amisulpride hydrochloride

Cat.No: T0811L

Synonym: APD-421,Amisulpride HCl,APD 421,APD421,Sultopride,氨磺必利盐酸盐

Cat.No: T29518

Synonym: LAS100977,LAS 100977,LAS-100977

L-796568 free base

Cat.No: T24380

Pirbuterol Acetate

Cat.No: T34079

Synonym: pirbuterol sulfate,EINECS 265-862-4,Maxair,Pirbuterol acetate (USAN)

L-796568 dihydrochloride

Cat.No: T27786

Synonym: L 796568,L-796568,L796568

Cat.No: T78567

Synonym: (±)-Moprolol

Target: Adrenergic Receptor

Cat.No: T69209

Cat.No: T70468

Cat.No: T69953

Trastuzumab beta

Cat.No: T76971

Galanin Receptor Ligand M35

Cat.No: TP1662

PD153035 nitrate

Cat.No: T69055

Disitertide diammonium

Cat.No: T75717

Disitertide TFA

Cat.No: T75716

Cat.No: T28157

Cefminox sodium

Cat.No: T65598

Cat. No.	Product Name	Target	Signaling Pathways
T1633	β-Carotene beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素	Apoptosis; ROS; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism
	β-Carotene (Provitamin A) 是一种天然存在的视黄醇（维生素 A）前体。它是一种 ROS 调节剂，具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂，可诱导乳腺癌细胞凋亡，具有抗癌活性。
T1048	Estradiol 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estradiol (E2) 是一种天然的类固醇性激素，对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
TJS0341	7-Amino-4-(trifluoromethyl)coumarin 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素	5-HT Receptor	GPCR/G Protein; Neuroscience
	7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物，其激发和发射波长分别为400和500 nm，可用来灵敏的检测蛋白酶。
T36914	2-Hydroxyanthraquinone	Others	Others
	2-Hydroxyanthraquinone 是一种天然产物，显示出抗肿瘤和免疫抑制活性。
T36295	Echistatin TFA
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...

天然产物

Cat.No: T1633

Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Target: Apoptosis, ROS, Endogenous Metabolite

Cat.No: T1048

Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

7-Amino-4-(trifluoromethyl)coumarin

Cat.No: TJS0341

Synonym: 香豆素151,Coumarin 151,AFC,7-氨基-4-（三氟甲基）香豆素

Target: 5-HT Receptor

2-Hydroxyanthraquinone

Cat.No: T36914

Target: Others

Cat.No: T36295

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04717	CD122/IL2RB Protein, Rhesus, Recombinant (His) interleukin 2 receptor, β,interleukin ...	Rhesus	HEK293 Cells
	CD122/IL2RB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.1 kDa and the accession number is H9Z8K1.
TMPY-05102	CD122/IL2RB Protein, Rat, Recombinant (His) interleukin 2 receptor, β,interleukin ...	Rat	HEK293 Cells
	CD122/IL2RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P26896.
TMPY-01767	IL-12RB2 Protein, Mouse, Recombinant (His) A930027I18Rik,interleukin 12 receptor<...	Mouse	HEK293 Cells
	IL-12RB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is P97378.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-05680	CD122/IL2RB Protein, Human, Recombinant (mFc) CD122,IL15RB,IL-15RB,interleukin 2	Human	HEK293 Cells
	CD122/IL2RB Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51 kDa and the accession number is P14784.
TMPY-05216	CD122/IL2RB Protein, Human, Recombinant (His) IL-15RB,interleukin 2 receptor, β,P70-75,I...	Human	Baculovirus Insect Cells
	CD122/IL2RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P14784.
TMPY-00860	CD122/IL2RB Protein, Human, Recombinant interleukin 2 receptor, β,interleukin ...	Human	HEK293 Cells
	CD122/IL2RB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is P14784.
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor <...	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-05784	CD122/IL2RB Protein, Mouse, Recombinant (hFc) IL-15Rβ,Il-2/15Rbeta,Il-2Rβ,inter...	Mouse	HEK293 Cells
	CD122/IL2RB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.76 kDa and the accession number is P16297.
TMPY-04031	CD122/IL2RB Protein, Mouse, Recombinant (His) IL-15Rβ,Il-2/15Rbeta,interleukin 2	Mouse	HEK293 Cells
	CD122/IL2RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16297.
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated IFN-R,interferon (α, β and Ω) receptor 2,I...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-00476	ITGB1 Protein, Human, Recombinant (His) VLAB,integrin, beta 1 (fibronectin receptor	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His) LDS2B,FAA3,TAAD2,MFS2,TGFR-2<...	Human	Baculovirus Insect Cells
	TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
TMPY-01650	CD131 Protein, Human, Recombinant (His) CDw131,IL5RB,colony stimulating factor 2 recept...	Human	HEK293 Cells
	CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1.
TMPY-04716	CD122/IL2RB Protein, Rhesus, Recombinant (hFc) interleukin 2 receptor, beta,inte...	Rhesus	HEK293 Cells
	CD122/IL2RB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.4 kDa and the accession number is H9Z8K1.
TMPY-04035	CD122/IL2RB Protein, Canine, Recombinant (hFc) interleukin 2 receptor, beta,inte...	Canine	HEK293 Cells
	CD122/IL2RB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is XP_003431552.1.
TMPY-05018	CD122/IL2RB Protein, Canine, Recombinant (His) interleukin 2 receptor, beta,inte...	Canine	HEK293 Cells
	CD122/IL2RB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is NP_001273779.1.
TMPJ-00326	CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated IL-2R subunit beta,High affinity IL-2<...	Human	HEK293 Cells
	Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit c...
TMPY-06428	IL-12RB2 Protein, Cynomolgus, Recombinant (mFc) interleukin 12 receptor, β2,inter...	Cynomolgus	HEK293 Cells
	IL-12RB2 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 94.93 kDa and the accession number is XP_005543136.1.
TMPJ-00398	IL-12RB2 Protein, Mouse, Recombinant (hFc) interleukin-12 receptor β-2 chain...	Mouse	HEK293 Cells
	The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits that are linked via disulfide bonds. Ligation of IL-12 to its receptor involves the binding of IL-12p35 to IL12RB1 and IL-12p40 to IL12RB2. This will result in the activation of tyrosine kinase 2 (TYK2), which is associated with the IL12RB1 chain and Janus kinase 2 (JAK2), which is ...
TMPJ-00290	GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) TRNR2,GDNFR-beta,TGF-β-related neurotrophi...	Human	HEK293 Cells
	GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kina...
TMPJ-00334	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) TGF-β receptor type II,Tgfbr2,TGF-β re...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPJ-00333	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Transforming growth factor-β receptor type II,T...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPY-00139	IFNAR2 Protein, Cynomolgus, Recombinant (His) interferon (α, β and Ω) receptor 2,interfe...	Cynomolgus	HEK293 Cells
	IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1.
TMPY-05027	PILRB Protein, Human, Recombinant (His) paired immunoglobin-like type 2 receptor β...	Human	HEK293 Cells
	PILRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9UKJ0-1.
TMPY-06515	CD122/IL2RB Protein, Human, Recombinant (His & Avi), Biotinylated P70-75,IL15RB,interleukin 2 receptor, ...	Human	HEK293 Cells
	CD122/IL2RB Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.73 kDa and the accession number is NP_000869.1.
TMPY-00859	CD122/IL2RB Protein, Human, Recombinant (hFc) IL-15RB,interleukin 2 receptor, beta	Human	HEK293 Cells
	CD122/IL2RB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.3 kDa and the accession number is P14784.
TMPY-02680	PILRB Protein, Mouse, Recombinant (hFc) FDFACT,paired immunoglobin-like type 2 receptor...	Mouse	HEK293 Cells
	PILRB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is Q2YFS2.
TMPH-01763	CHRNB2 Protein, Human, Recombinant (His & V5) CHRNB2,Neuronal acetylcholine receptor sub...	Human	E. coli
	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. CHRNB2 Protein, Human, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 31.9 kDa and the accession number is P17787.
TMPY-06821	THRB Protein, Human, Recombinant (His) THRB1,GRTH,THR1,ERBA2,C-ERBA-2,THRB2	Human	E. coli
	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and pituitary, respectively. THRB regulates the feedback of T3-dependent thyrotropin-stimulating hormone (TSH) transcription in the pituitary by binding to thyroid hormone (TH) response elements present...
TMPJ-00213	IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc) Cytokine receptor family 2 member 4,Interl...	Human	HEK293 Cells
	Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal...
TMPY-04283	CD131 Protein, Rat, Recombinant (hFc) colony stimulating factor 2 receptor, ...	Rat	HEK293 Cells
	CD131 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.1 kDa and the accession number is Q78ZF5.
TMPK-00889	IFNAR2 Protein, Human, Recombinant (aa 27-243, His) IFN-alpha/beta R2,IFNAR2,IFNbR	Human	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t...
TMPK-00637	IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) β receptor10,IFNbR2,IFN α/β R2,IF...	Cynomolgus	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-...
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His) IFNARB,IFNABR,interferon (α, β and ω) receptor ...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc) interferon (α, β and ω) receptor 2,IFNABR,...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1,VLA-4 Subunit β,Fibronectin Rec...	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree...
TMPH-00957	ARNT Protein, Human, Recombinant (His) Hypoxia-inducible factor 1-beta,Class E basic helix...	Human	P. pastoris (Yeast)
	ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-05508	TGFBR2 Protein, Human, Recombinant (hFc) TGFβ-RII,TGFbeta-RII,MFS2,AAT3,transformin...	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173.
TMPY-05810	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated RIIC,TAAD2,AAT3,TGFβ-RII,FAA3,transforming growth f...	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173.
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His) IFN-al,CRF2-1,IFN-alpha/beta receptor<...	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPJ-00274	LTBR Protein, Human, Recombinant (His) TNFCR,Tumor Necrosis Factor Receptor Superfamily Me...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand p...
TMPY-05716	Integrin alpha V beta 3 Protein, Human, Recombinant (His) Integrin α V β 3,Integrin alpha V β3	Human	HEK293 Cells
	Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant transforming growth factor β-2,BSC-1 cell growth in...	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPJ-01461	IL-15RA & IL-15 Protein, Human, Recombinant (hFc) IL-15 Receptor α & IL-15 Fusion Protein,Interleukin...	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPJ-01462	IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc) IL15,IL15RA&IL15,IL-15,Interleukin-15,IL-15 Receptor	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ...
TMPJ-00154	IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells) sIL-15 receptor subunit α,Il15ra,Interleukin-15	Mouse	HEK293 Cells
	Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPJ-01210	IL-33 Protein, Mouse, Recombinant Interleukin-1 family member 11,白细胞介素,NF-HEV and IL- 1F11,白介素...	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ...
TMPK-00507	TREM2 Protein, Cynomolgus, Recombinant (His) TREM2,Trem2a,PLOSL2,TREM-2	Cynomolgus	HEK293 Cells
	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote...
TMPY-02388	SIRP beta 1 Protein, Mouse, Recombinant (His) SIRP-beta,SIRP-β,99327N5Rik,Sirpb,Sirpb1,S...	Mouse	HEK293 Cells
	SIRPB1A (Signal-regulatory protein beta 1A), also known as SIRP beta 1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. Signal-regulatory proteins (SIRPs) are cell-surface glycoproteins expressed on myeloid and neural cells that have been shown to recruit SH2 domain-containing protein phosphatase 1 (SHP-1) and SHP-2 and to regulate receptor tyrosine kinase-coupled signaling. SIRP are classified as SIRP alpha molecules, containing 11- to 113-amino acid long, or...
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重组蛋白

CD122/IL2RB Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04717

Species: Rhesus

Expression System: HEK293 Cells

CD122/IL2RB Protein, Rat, Recombinant (His)

Cat.No: TMPY-05102

Species: Rat

Expression System: HEK293 Cells

IL-12RB2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01767

Species: Mouse

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05680

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (His)

Cat.No: TMPY-05216

Species: Human

Expression System: Baculovirus Insect Cells

CD122/IL2RB Protein, Human, Recombinant

Cat.No: TMPY-00860

Species: Human

Expression System: HEK293 Cells

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05784

Species: Mouse

Expression System: HEK293 Cells

CD122/IL2RB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04031

Species: Mouse

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04799

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00476

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05157

Species: Human

Expression System: Baculovirus Insect Cells

CD131 Protein, Human, Recombinant (His)

Cat.No: TMPY-01650

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-04716

Species: Rhesus

Expression System: HEK293 Cells

CD122/IL2RB Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-04035

Species: Canine

Expression System: HEK293 Cells

CD122/IL2RB Protein, Canine, Recombinant (His)

Cat.No: TMPY-05018

Species: Canine

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

Cat.No: TMPJ-00326

Species: Human

Expression System: HEK293 Cells

IL-12RB2 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-06428

Species: Cynomolgus

Expression System: HEK293 Cells

IL-12RB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00398

Species: Mouse

Expression System: HEK293 Cells

GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00290

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

Cat.No: TMPJ-00334

Species: Mouse

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Cat.No: TMPJ-00333

Species: Mouse

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00139

Species: Cynomolgus

Expression System: HEK293 Cells

PILRB Protein, Human, Recombinant (His)

Cat.No: TMPY-05027

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06515

Species: Human

Expression System: HEK293 Cells

CD122/IL2RB Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00859

Species: Human

Expression System: HEK293 Cells

PILRB Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02680

Species: Mouse

Expression System: HEK293 Cells

CHRNB2 Protein, Human, Recombinant (His & V5)

Cat.No: TMPH-01763

Species: Human

Expression System: E. coli

THRB Protein, Human, Recombinant (His)

Cat.No: TMPY-06821

Species: Human

Expression System: E. coli

IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00213

Species: Human

Expression System: HEK293 Cells

CD131 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04283

Species: Rat

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

Cat.No: TMPK-00889

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

Cat.No: TMPK-00637

Species: Cynomolgus

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01642

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01640

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (aa 21-728, His)

Cat.No: TMPJ-00786

Species: Human

Expression System: HEK293 Cells

ARNT Protein, Human, Recombinant (His)

Cat.No: TMPH-00957

Species: Human

Expression System: P. pastoris (Yeast)

TGFBR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05508

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated

Cat.No: TMPY-05810

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00331

Species: Rhesus

Expression System: HEK293 Cells

LTBR Protein, Human, Recombinant (His)

Cat.No: TMPJ-00274

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-05716

Species: Human

Expression System: HEK293 Cells

TGF beta 2 Protein, Mouse/Rat, Recombinant

Cat.No: TMPJ-00261

Species: Mouse,Rat

Expression System: HEK293 Cells

IL-15RA & IL-15 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01461

Species: Human

Expression System: HEK293 Cells

IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

Cat.No: TMPJ-01462

Species: Human

Expression System: HEK293 Cells

IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-00154

Species: Mouse

Expression System: HEK293 Cells

IL-33 Protein, Mouse, Recombinant

Cat.No: TMPJ-01210

Species: Mouse

Expression System: E. coli

TREM2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00507

Species: Cynomolgus

Expression System: HEK293 Cells

SIRP beta 1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02388

Species: Mouse

Expression System: HEK293 Cells

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